GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration
These findings underscore the role of GPR15LG in inflammation and metastasis, offering potential therapeutic avenues for CXCR4-mediated diseases.
Authors
- Julio Vieyto‐Nuñez (ORCID: https://orcid.org/0000-0002-3128-6764)
- Mirja Harms (ORCID: https://orcid.org/0000-0002-5460-5166)
- Stephan Stilgenbauer (ORCID: https://orcid.org/0000-0002-6830-9296)
- Christian Buske (ORCID: https://orcid.org/0000-0002-9782-9012)
- Dan Albers (ORCID: https://orcid.org/0000-0002-5863-6322)
- Andy Chevigné (ORCID: https://orcid.org/0000-0003-4768-6743)
- Billy Michael Chelliah Jebaraj (ORCID: https://orcid.org/0000-0002-6188-1652)
- Chiara Pastorio (ORCID: https://orcid.org/0000-0002-4745-3678)
- Julia Zinngrebe
- Moumita Datta (ORCID: https://orcid.org/0009-0004-6524-4804)
- Elsa Sánchez‐García (ORCID: https://orcid.org/0000-0002-9211-5803)
- Pamela Fischer‐Posovszky (ORCID: https://orcid.org/0000-0003-3402-9840)
- Ulrich Stifel (ORCID: https://orcid.org/0000-0001-8535-8156)
- Pascal von Maltitz (ORCID: https://orcid.org/0000-0003-0533-6999)
- Palash Chandra Maity (ORCID: https://orcid.org/0000-0003-3295-5859)
- Jan Münch (ORCID: https://orcid.org/0000-0001-7316-7141)
- Frank Kirchhoff (ORCID: https://orcid.org/0000-0002-7052-2360)
- Yasser Almeida‐Hernández (ORCID: https://orcid.org/0000-0001-9832-3534)
- Hassan Jumaa (ORCID: https://orcid.org/0000-0003-3383-141X)
- Dana Weiß (ORCID: https://orcid.org/0000-0002-6045-8086)
- Manish Kumar (ORCID: https://orcid.org/0000-0003-2472-8277)
- S. V. Novikova
- Janeni Jaikishan
- Florian Klassen
Institutions
- Universität Ulm (DE)
- TU Dortmund University (DE)
- German Center for Pediatric and Adolescent Rheumatology (DE)
- Luxembourg Institute of Health (LU)
- University Hospital Ulm (DE)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s12964-025-02231-x
- Citations
- 1
- Primary Topic
- Chemokine receptors and signaling
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Baden-Württemberg Stiftung
- Deutsche Forschungsgemeinschaft
- Fonds National de la Recherche Luxembourg
- Korea University
- Fonds De La Recherche Scientifique - FNRS
- Fritz Thyssen Stiftung
- Universität Ulm
- European Social Fund