Real-World Experience with Triplet Therapy for High-Volume Metastatic Castration-Sensitive Prostate Cancer: A Retrospective Cohort Study from a Japanese Academic Hospital
While PSA responses were favorable and tolerability was generally high, progression patterns and subsequent therapies varied widely, highlighting the need for close monitoring and individualized treatment in patients with mCSPC receiving triplet therapy.
Authors
- Yoichiro Yamamoto (ORCID: https://orcid.org/0000-0003-0799-4338)
- Yuka Toyama
- Jun Akatsuka (ORCID: https://orcid.org/0000-0002-2671-7064)
- Hikaru Mikami (ORCID: https://orcid.org/0009-0001-5555-5789)
- Kotaro Obayashi (ORCID: https://orcid.org/0009-0001-0427-0644)
- Yukihiro Kondo (ORCID: https://orcid.org/0000-0003-4141-9230)
- Go Kimura (ORCID: https://orcid.org/0000-0003-0088-9324)
- Yuki Endo (ORCID: https://orcid.org/0009-0002-0787-9321)
- Shogo Imai
- Hiroya Hasegawa
- Hayato Takeda (ORCID: https://orcid.org/0000-0002-4556-6601)
- Mami Takadate
Institutions
- Tohoku University (JP)
- RIKEN Center for Advanced Intelligence Project (JP)
- Nippon Medical School (JP)
Publication Details
- Journal
- Journal of Nippon Medical School
- Published
- 2025-04-20
- DOI
- https://doi.org/10.1272/jnms.jnms.2025_92-212
- Citations
- 1
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Japan Society for the Promotion of Science
- Moonshot Research and Development Program