Analytical quality control in targeted lipidomics: Evaluating the performance of commercial plasma as a surrogate for pooled study samples
This study provides a comprehensive comparison of QC strategies and emphasizes the importance of careful QC workflow selection. While PQCs offer advantages, sQCs serve as a suitable alternative for quality assessment and pre-processing. Their commercial availability also supports use as intra- and inter-laboratory long-term references, aiding data harmonization across studies and laboratories.
Authors
- Emad El‐Omar (ORCID: https://orcid.org/0000-0002-0011-3924)
- Ferdous Ahmed Sohel (ORCID: https://orcid.org/0000-0003-1557-4907)
- Alanah Grant-St James (ORCID: https://orcid.org/0000-0002-9234-805X)
- Amanda Henry (ORCID: https://orcid.org/0000-0002-7351-8922)
- Jeremy K. Nicholson (ORCID: https://orcid.org/0000-0002-8123-8349)
- Alex J. Lee (ORCID: https://orcid.org/0000-0002-0355-7248)
- Luke Whiley (ORCID: https://orcid.org/0000-0002-9088-4799)
- Aude-Claire Morillon (ORCID: https://orcid.org/0000-0002-9692-9396)
- Julien Wist (ORCID: https://orcid.org/0000-0002-3416-2572)
- Elaine Holmes (ORCID: https://orcid.org/0000-0002-0556-8389)
- Ruey Leng Loo (ORCID: https://orcid.org/0000-0001-5307-5709)
- Bu B. Yeap (ORCID: https://orcid.org/0000-0002-7612-5892)
- Nicola Gray (ORCID: https://orcid.org/0000-0002-0094-5245)
- Kok Wai Wong (ORCID: https://orcid.org/0000-0001-8767-1031)
- Daniella Susic (ORCID: https://orcid.org/0000-0002-5607-5154)
Institutions
- New South Wales Department of Health (AU)
- Murdoch University (AU)
- Sutherland Hospital (AU)
- Fiona Stanley Hospital (AU)
- UNSW Sydney (AU)
- The George Institute for Global Health (AU)
Publication Details
- Journal
- Analytica Chimica Acta
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1016/j.aca.2025.344225
- Citations
- 2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.61