HERMES: Randomized Trial of 2-Fraction or 5-Fraction Magnetic Resonance Imaging–Guided Adaptive Prostate Radiation Therapy
Acceptable acute GU toxicity was seen after 2-fraction SBRT. Acute GI toxicity was low. Randomized trials are warranted to explore late toxicity and biochemical control.
Authors
- Ragu Ratnakumaran
- Angela Pathmanathan
- Aidan Adkins
- Derek Price
- S. Hafeez (ORCID: https://orcid.org/0000-0002-2057-0946)
- Alison Tree (ORCID: https://orcid.org/0000-0002-5033-424X)
- Chris Parker
- Stephanie Burnett
- Rosalyne Westley (ORCID: https://orcid.org/0000-0001-5242-8736)
- Katie Biscombe (ORCID: https://orcid.org/0009-0002-9298-3093)
- Alex Dunlop (ORCID: https://orcid.org/0009-0002-9105-3249)
- Nina Tunariu (ORCID: https://orcid.org/0000-0001-6656-3699)
- Trina Herbert (ORCID: https://orcid.org/0000-0001-7542-0622)
- Greta Bucinskaite
- S. Alexander (ORCID: https://orcid.org/0000-0002-3916-5174)
- Helena M. Verkooijen (ORCID: https://orcid.org/0000-0001-9480-1623)
- Uwe Oelfke (ORCID: https://orcid.org/0000-0003-2309-0814)
- Simeon Nill (ORCID: https://orcid.org/0000-0003-4351-8136)
- Julia Murray (ORCID: https://orcid.org/0000-0003-3550-6178)
- Georgina Manning (ORCID: https://orcid.org/0000-0003-2198-0880)
- Anna Wilkins (ORCID: https://orcid.org/0000-0002-0425-584X)
- Adam Mitchell (ORCID: https://orcid.org/0000-0001-6736-3349)
- Sian Cooper (ORCID: https://orcid.org/0009-0001-1016-9841)
- Emma Hall (ORCID: https://orcid.org/0009-0002-0026-974X)
Institutions
- Royal Marsden NHS Foundation Trust (GB)
- Institute of Cancer Research (GB)
- University Medical Center Utrecht (NL)
- Royal Marsden Hospital (GB)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.05.008
- Citations
- 5
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 7.59
Funders
- AstraZeneca
- Royal Marsden NHS Foundation Trust
- Accuray
- Veracyte
- Cancer Research UK
- National Institute for Health and Care Research
- Siemens Healthineers
- Genentech
- Medical Research Council
- Cilag