Genomic investigation of NDM-1 producing Enterobacterales transmission in a South Korean hospital
This study highlights the dual roles of clonal spread and plasmid-mediated horizontal gene transfer in the dissemination of bla<sub>NDM-1</sub> in hospital settings. The persistence of highly conserved IncX3 plasmids in environmental isolates underscores the complexity of carbapenem resistance control. Comprehensive infection control strategies targeting patient-to-patient transmission and environmental reservoirs are crucial for mitigating the spread of NDM-producing Enterobacterales.
Authors
- Sun Hee Park (ORCID: https://orcid.org/0000-0001-5648-9237)
- Jeong-Ih Shin (ORCID: https://orcid.org/0000-0003-3902-8417)
- Chulmin Park (ORCID: https://orcid.org/0000-0001-9147-0478)
- Seung-Hyun Jung (ORCID: https://orcid.org/0000-0002-9870-0923)
- Dong‐Gun Lee (ORCID: https://orcid.org/0000-0003-4655-0641)
Institutions
- Catholic University of Korea (KR)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1016/j.jgar.2025.05.010
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00