Immunophenotypic and Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in Bullous Pemphigoid
BP patients show distinct immune dysregulation, including decreased CD4⁺ T cells, Th2, and B cells, increased M2a-like monocytes, altered gene expression profiles, and correlations between PSTPIP2, SAMSN1 and disease activity. These findings provide insights into pathogenesis and potential therapeutic targets of BP.
Authors
- Min-Sung Kim (ORCID: https://orcid.org/0000-0002-7757-7970)
- You Won Choi (ORCID: https://orcid.org/0000-0001-6315-3889)
- Jae‐Yong Nam (ORCID: https://orcid.org/0000-0001-8318-2724)
- Jeewoo Choi (ORCID: https://orcid.org/0009-0003-7879-7988)
- Ji Yeon Byun (ORCID: https://orcid.org/0000-0003-4519-9474)
- Hae Young Choi (ORCID: https://orcid.org/0000-0003-3460-2539)
Institutions
- Ewha Womans University (KR)
- Corestem (South Korea) (KR)
Publication Details
- Journal
- Annals of Dermatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5021/ad.25.032
- Primary Topic
- Autoimmune Bullous Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00