WT1 pathogenic variant in azoospermic infertile men with an isolated undescended testis
The rs587776576 mutation is pathogenic. It exhibited a significant association (p=0.022), indicating its association with infertility and UDT in the Iranian population. This research could broaden the spectrum of WT1 variations and underscore the importance of these variants in the genetic etiology of UDT and infertility. These findings provide a foundation for clinical diagnosis and genetic counseling.
Authors
- Parnaz Borjian Boroujeni (ORCID: https://orcid.org/0000-0002-2215-2967)
- Anahita Mohseni Meybodi (ORCID: https://orcid.org/0000-0001-9049-8057)
- Kaveh Haratian
- Neda Sharifi
- Marjan Sabbaghian (ORCID: https://orcid.org/0000-0001-9439-268X)
Institutions
- University of Science and Culture (IR)
- Western University (CA)
- Royan Institute (IR)
- Academic Center for Education, Culture and Research (IR)
Publication Details
- Journal
- Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine
- Published
- 2025-05-20
- DOI
- https://doi.org/10.5653/cerm.2024.07584
- Citations
- 1
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Royan Institute