Obtaining Valid Compatibility Intervals for Sequence Symmetry Analyses Utilizing Active Comparators: A Simulation Study

The Miettinen-Nurminen score estimator provided the most accurate coverage for 95% CIs of active comparator SRs, especially with low sample sizes. Therefore, we recommend using the Miettinen-Nurminen score estimator for active comparator SRs.

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Publication Details

Journal
Pharmacoepidemiology and Drug Safety
Published
2025-05-20
DOI
https://doi.org/10.1002/pds.70160
Primary Topic
Statistical Methods in Clinical Trials
Type
article
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article

Obtaining Valid Compatibility Intervals for Sequence Symmetry Analyses Utilizing Active Comparators: A Simulation Study

Martin Torp Rahbek, Lars Christian Lund, Jesper Hallas
Pharmacoepidemiology and Drug Safety
Statistical Methods in Clinical Trials
article

Obtaining Valid Compatibility Intervals for Sequence Symmetry Analyses Utilizing Active Comparators: A Simulation Study

Martin Torp Rahbek, Lars Christian Lund, Jesper Hallas
article en

Abstract

The Miettinen-Nurminen score estimator provided the most accurate coverage for 95% CIs of active comparator SRs, especially with low sample sizes. Therefore, we recommend using the Miettinen-Nurminen score estimator for active comparator SRs.

Pharmacoepidemiology and Drug SafetyVol. 34(6)
University of Southern Denmark (DK)
Good health and well-being
Openalex Percentile: Top 89%
Statistical Methods in Clinical Trials
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