Liver Transplantation in Primary Hyperoxaluria: A Single‐Center 10‐Year Experience

PHs is a rare metabolic disorder, and LT significantly improves both survival and quality of life for affected patients. In our cohort, the majority of patients exhibited favorable long-term outcomes, along with a notable reduction in urine oxalate levels post-transplantation. However, challenges persist, including graft shortages and the risk of renal graft loss due to oxalosis, which continue to affect overall treatment outcomes. These findings highlight the importance of close monitoring and multidisciplinary care in managing PH patients' post-transplant.

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Publication Details

Journal
Pediatric Transplantation
Published
2025-05-20
DOI
https://doi.org/10.1111/petr.70102
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Liver Transplantation in Primary Hyperoxaluria: A Single‐Center 10‐Year Experience

Zahra Beyzaei, Kourosh Kazemi, Alireza Shamsaeefar, Saman Nikeghbalian et al.
1 links
Pediatric Transplantation
Kidney Stones and Urolithiasis Treatments
article

Liver Transplantation in Primary Hyperoxaluria: A Single‐Center 10‐Year Experience

Zahra Beyzaei, Kourosh Kazemi, Alireza Shamsaeefar, Saman Nikeghbalian, Bita Geramizadeh, Masoud Dehghani, Ali Bahador, S A Malek-Hosseini, Kiana Ghatei
article en

Abstract

PHs is a rare metabolic disorder, and LT significantly improves both survival and quality of life for affected patients. In our cohort, the majority of patients exhibited favorable long-term outcomes, along with a notable reduction in urine oxalate levels post-transplantation. However, challenges persist, including graft shortages and the risk of renal graft loss due to oxalosis, which continue to affect overall treatment outcomes. These findings highlight the importance of close monitoring and multidisciplinary care in managing PH patients' post-transplant.

Pediatric TransplantationVol. 29(4)
Shiraz University of Medical Sciences (IR), Sina Hospital (IR)
Shiraz University of Medical Sciences
Good health and well-being
Openalex Percentile: Top 82%
Kidney Stones and Urolithiasis Treatments
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Liver Transplantation in Primary Hyperoxaluria: A Single‐Center 10‐Year Experience — Zahra Beyzaei, Kourosh Kazemi, et al. · Pediatric Transplantation (2025) | TGRS Research Map | TGRS