Investigating the Role of Ferroptosis in Soman-Induced Neurotoxicity: A Pathway to New Potential Therapeutic Targets
These findings indicate that ferroptosis engages in the course of neurotoxicity caused by soman and exerts a harmful effect via the glutamate/xCT/GPX4 pathway. This study provides new potential therapeutic targets for countermeasures against soman exposure.
Authors
- Xinjian Yang (ORCID: https://orcid.org/0000-0001-7306-0125)
- Yuheng Shan
- Tiantian Zhuang
- Jiatang Zhang (ORCID: https://orcid.org/0000-0002-9714-0944)
- Mengyao Wang (ORCID: https://orcid.org/0009-0008-4446-0056)
- Jiahua Zhao (ORCID: https://orcid.org/0009-0009-9242-5631)
- Xiaojiao Xu
- Zhiyong Nie
Institutions
- Henan University (CN)
- Academy of Military Medical Sciences (CN)
- Chinese PLA General Hospital (CN)
- Chinese People's Armed Police Force Medical College Affiliated Hospital (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537196.77
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00