Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization
Irisin exhibits potent anti-cancer effects on cervical cancer cells by modulating several key cellular processes and altering the tumor microenvironment. Irisin effectively inhibits the proliferation, invasion, and migration of cervical cancer cells and affects the levels of autophagy and apoptosis. Furthermore, it inhibits cancer cells by affecting the polarization of tumor-associated macrophages, underscoring their potential as a novel therapeutic target for treating cervical cancer.
Authors
- Xiaojie Ma
- Guangwen Cao (ORCID: https://orcid.org/0000-0002-8094-1278)
- Wei Yan (ORCID: https://orcid.org/0000-0002-6735-6066)
Institutions
- Jiangxi Pingxiang People's Hospital (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537196.84
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00