Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway
This study showed that nesfatin-1 reduces neutrophils and suppresses inflammation via the HMGB-1/TLR4/Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-κB)/NLRP3 pathway, suggesting its potential clinical application in the treatment of BPD.
Authors
- Feifeng Lou (ORCID: https://orcid.org/0000-0003-0934-4128)
- Xiaoting Yang (ORCID: https://orcid.org/0000-0002-4177-4876)
- Gang Luo
Institutions
- Quzhou College of Technology (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Zhuhai People's Hospital (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537196.83
- Citations
- 2
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04