Spermine Enhances Cholesterol Effluence of Macrophages Through Caspase 2-Mediated Autophagy
SPM promotes autophagy to enhance the cholesterol efflux of THP-1 cell-derived macrophages by downregulating <i>CASP2</i> expression.
Authors
- Daohai Chen
- Yifan Mao (ORCID: https://orcid.org/0000-0001-5589-8987)
- Xinyue Yuan
- Jun Zhuang (ORCID: https://orcid.org/0000-0001-7915-7497)
- Yuqiao Chen
- Xiaolong Li (ORCID: https://orcid.org/0009-0006-9431-8336)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- Changzhou No.2 People's Hospital (CN)
- Changzhou University (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537196.78
- Citations
- 1
- Primary Topic
- Polyamine Metabolism and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Government of Jiangsu Province