Copper-catalyzed three-component radical aminoazolation of vinylarenes with <i>N</i>-fluorobenzenesulfonimide and trimethylsilylazole derivatives
A copper-catalyzed three-component radical aminoazolation of vinylarenes with <i>N</i>-fluorobenzenesulfonimide (NFSI) and trimethylsilylazole derivatives has been developed. This methodology provides an efficient and straightforward approach to generate various β-sulfoamino azoles in good to excellent yields. The protocol features exclusive chemo- and regioselectivity, and excellent functional group tolerance under mild conditions.
Authors
- Y. W. Bao (ORCID: https://orcid.org/0000-0001-8918-5248)
- Qingbing Yuan (ORCID: https://orcid.org/0000-0002-1901-6542)
- Zeming Huang (ORCID: https://orcid.org/0009-0007-5786-1169)
- Yun Wei (ORCID: https://orcid.org/0000-0002-8639-0067)
- Hua Wang (ORCID: https://orcid.org/0000-0002-7150-5247)
- Shaowu Wang (ORCID: https://orcid.org/0000-0003-1083-1468)
- Cheng Wu
Institutions
- Anhui Normal University (CN)
- Anhui Polytechnic University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc01080b
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Anhui Provincial Department of Science and Technology
- Key Research and Development Program of Wuhu