Urgent Use of Sugammadex in a Patient With Occult Bronchopleural Fistula Manifested Following Anesthesia Induction

Sugammadex could play a significant role in managing the "cannot intubate, cannot ventilate" scenarios. However, the urgent use of sugammadex in intubated patients after induction of anesthesia is uncommon. We report the case of an 85-year-old, 45 kg man with a history of pulmonary resection for lung cancer and open window thoracostomy for postoperative pyothorax. He underwent a ureteral stent exchange for ureteral calculi. During anesthesia induction, 40 mg of rocuronium was administered, followed by uneventful mask ventilation and tracheal intubation. Subsequent mechanical ventilation failed due to massive air leakage from an occult bronchopleural fistula in the left chest wall that manifested following anesthesia induction. However, oxygenation was maintained with oxygen-air insufflation from the anesthesia machine by closing the adjustable pressure-limiting valve and maximizing fresh gas flow. Although the tracheal tube was blindly advanced with the intention of one-lung ventilation via the right lung, it was unsuccessful. Subsequently, 200 mg of sugammadex was administered to reverse the rocuronium effect, allowing the continuation of anesthesia with desflurane under spontaneous breathing. High-flow oxygen-air insufflation via a tracheal tube and urgent, but not critical, use of sugammadex to restore spontaneous breathing were helpful for the anesthetic management of this patient who developed a massive air leak due to an occult bronchopleural fistula that manifested following anesthesia induction.

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Publication Details

Journal
Cureus
Published
2025-05-19
DOI
https://doi.org/10.7759/cureus.84431
Primary Topic
Airway Management and Intubation Techniques
Type
article
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article

Urgent Use of Sugammadex in a Patient With Occult Bronchopleural Fistula Manifested Following Anesthesia Induction

Reina Sakazaki, Daiki Nagane, Takashi Suzuki, Mizue Ishii et al.
Cureus
Airway Management and Intubation Techniques
article

Urgent Use of Sugammadex in a Patient With Occult Bronchopleural Fistula Manifested Following Anesthesia Induction

Reina Sakazaki, Daiki Nagane, Takashi Suzuki, Mizue Ishii, Akiko Ogaku
article en

Abstract

Sugammadex could play a significant role in managing the "cannot intubate, cannot ventilate" scenarios. However, the urgent use of sugammadex in intubated patients after induction of anesthesia is uncommon. We report the case of an 85-year-old, 45 kg man with a history of pulmonary resection for lung cancer and open window thoracostomy for postoperative pyothorax. He underwent a ureteral stent exchange for ureteral calculi. During anesthesia induction, 40 mg of rocuronium was administered, followed by uneventful mask ventilation and tracheal intubation. Subsequent mechanical ventilation failed due to massive air leakage from an occult bronchopleural fistula in the left chest wall that manifested following anesthesia induction. However, oxygenation was maintained with oxygen-air insufflation from the anesthesia machine by closing the adjustable pressure-limiting valve and maximizing fresh gas flow. Although the tracheal tube was blindly advanced with the intention of one-lung ventilation via the right lung, it was unsuccessful. Subsequently, 200 mg of sugammadex was administered to reverse the rocuronium effect, allowing the continuation of anesthesia with desflurane under spontaneous breathing. High-flow oxygen-air insufflation via a tracheal tube and urgent, but not critical, use of sugammadex to restore spontaneous breathing were helpful for the anesthetic management of this patient who developed a massive air leak due to an occult bronchopleural fistula that manifested following anesthesia induction.

CureusVol. 17(5)
National Cancer Center (US), SHOWA Medical University Hospital (JP)
Openalex Percentile: Top 80%
Airway Management and Intubation Techniques
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