Efficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial Hypercholesterolemia: Results From the Double-Blind, Placebo-Controlled Part of the ORION-13 Randomized Trial

Authors

Anja Schweizer (ORCID: https://orcid.org/0000-0001-8787-3442)
Albert Wiegman (ORCID: https://orcid.org/0000-0001-6223-5671)
Amy L. Peterson (ORCID: https://orcid.org/0000-0002-5238-3002)
Robert A. Hegele (ORCID: https://orcid.org/0000-0003-2861-5325)
Éric Bruckert (ORCID: https://orcid.org/0000-0002-4527-9629)
Anastasia Lesogor
Joep C. Defesche (ORCID: https://orcid.org/0000-0003-3707-8277)
Yibo Wang (ORCID: https://orcid.org/0000-0001-9662-2602)

Institutions

Western University (CA)
Novartis (Switzerland) (CH)
University of Wisconsin–Madison (US)
Amsterdam UMC Location University of Amsterdam (NL)
Novartis (China) (CN)
Centre de Recherche Médecine, Sciences, Santé, Santé Mentale, Société (FR)
Wisconsin Division of Public Health (US)
Amsterdam University Medical Centers (NL)
University of Amsterdam (NL)

Publication Details

Journal: Circulation
Published: 2025-05-20
DOI: https://doi.org/10.1161/circulationaha.124.073233
Citations: 10
Primary Topic: Lipoproteins and Cardiovascular Health
Type: article
Field-Weighted Citation Impact: 20.06

Funders

Novartis Pharma

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article

Efficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial Hypercholesterolemia: Results From the Double-Blind, Placebo-Controlled Part of the ORION-13 Randomized Trial

Anja Schweizer, Albert Wiegman, Amy L. Peterson, Robert A. Hegele et al.

May 20, 2025

10 citations

Circulation

Lipoproteins and Cardiovascular Health

20.06

article

Efficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial Hypercholesterolemia: Results From the Double-Blind, Placebo-Controlled Part of the ORION-13 Randomized Trial

Anja Schweizer, Albert Wiegman, Amy L. Peterson, Robert A. Hegele, Éric Bruckert, Anastasia Lesogor, Joep C. Defesche, Yibo Wang

May 20, 2025article en

10 citations

Abstract

No abstract available for this paper.

CirculationVol. 151(25)

Western University (CA), Novartis (Switzerland) (CH), University of Wisconsin–Madison (US), Amsterdam UMC Location University of Amsterdam (NL), Novartis (China) (CN), Centre de Recherche Médecine, Sciences, Santé, Santé Mentale, Société (FR), Wisconsin Division of Public Health (US), Amsterdam University Medical Centers (NL), University of Amsterdam (NL)

Novartis Pharma

Good health and well-being

Openalex Percentile: Top 0%

Lipoproteins and Cardiovascular Health

20.06

DOI Open Access PDF OpenAlex

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Efficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial Hypercholesterolemia: Results From the Double-Blind, Placebo-Controlled Part of the ORION-13 Randomized Trial — Anja Schweizer, Albert Wiegman, et al. · Circulation (2025) | TGRS Research Map | TGRS