“K-cramps”: ketamine misuse and abdominal pain

Ketamine is an N-methyl-D-aspartate glutamate receptor antagonist used primarily as an anaesthetic agent and analgesic. Recreational use in the UK became widespread in the 1990s and recent evidence shows a preponderance in 16–24 year olds. Its hallucinogenic and dissociative effects are the likely cause of its popularity as a recreational drug. Ketamine, when used recreationally, is often inhaled, snorted and rarely ingested orally. This report describes a case of recurrent abdominal pain due to ketamine misuse, colloquially named “K-cramps”, exploring its clinical presentation, the diagnostic process and potential management strategies for this underreported condition.

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Publication Details

Journal
Frontline Gastroenterology
Published
2025-05-19
DOI
https://doi.org/10.1136/flgastro-2024-102928
Primary Topic
Treatment of Major Depression
Type
article
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article

“K-cramps”: ketamine misuse and abdominal pain

Abisoye Akintimehin, Jonathan M. Hoare
Frontline Gastroenterology
Treatment of Major Depression
article

“K-cramps”: ketamine misuse and abdominal pain

Abisoye Akintimehin, Jonathan M. Hoare
article en

Abstract

Ketamine is an N-methyl-D-aspartate glutamate receptor antagonist used primarily as an anaesthetic agent and analgesic. Recreational use in the UK became widespread in the 1990s and recent evidence shows a preponderance in 16–24 year olds. Its hallucinogenic and dissociative effects are the likely cause of its popularity as a recreational drug. Ketamine, when used recreationally, is often inhaled, snorted and rarely ingested orally. This report describes a case of recurrent abdominal pain due to ketamine misuse, colloquially named “K-cramps”, exploring its clinical presentation, the diagnostic process and potential management strategies for this underreported condition.

Frontline Gastroenterology
Imperial College Healthcare NHS Trust (GB)
Openalex Percentile: Top 87%
Treatment of Major Depression
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“K-cramps”: ketamine misuse and abdominal pain — Abisoye Akintimehin, Jonathan M. Hoare · Frontline Gastroenterology (2025) | TGRS Research Map | TGRS