Prevalence of high N-terminal prohormone of brain natriuretic peptide levels and associated factors among community-dwelling older adults aged over 75 years (The SONIC study): a cross-sectional study

A cross-sectional analysis revealed that 52.0% of 611 participants had NT-proBNP ≥ 125 pg/mL. Multinomial logistic regression analysis showed that female sex, older age (80s and 90s), and uncontrolled high blood pressure were significantly associated with 125 ≤ NT-proBNP < 300 pg/mL, while older age (80s and 90s), coronary artery disease, atrial fibrillation, and renal dysfunction were significantly associated with NT-proBNP ≥ 300 pg/mL. Independent association between higher salt intake and NT-proBNP ≥ 300 pg/mL was also observed. Appropriate management of common HF risk factors, such as uncontrolled high blood pressure and high salt intake, is crucial to prevent the progression of overt HF.

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Publication Details

Journal
BMC Research Notes
Published
2025-05-20
DOI
https://doi.org/10.1186/s13104-025-07280-6
Citations
1
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
1.39

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article

Prevalence of high N-terminal prohormone of brain natriuretic peptide levels and associated factors among community-dwelling older adults aged over 75 years (The SONIC study): a cross-sectional study

Yuya Akagi, Yukie Masui, Hiroshi Akasaka, Kazunori Ikebe et al.
1 citations
BMC Research Notes
Heart Failure Treatment and Management
1.39
article

Prevalence of high N-terminal prohormone of brain natriuretic peptide levels and associated factors among community-dwelling older adults aged over 75 years (The SONIC study): a cross-sectional study

Yuya Akagi, Yukie Masui, Hiroshi Akasaka, Kazunori Ikebe, Michiko Kido, Yoichi Takami, Yasuyuki Gondo, Kayo Godai, Yasumichi Arai, Takeshi Nakagawa, Kei Kamide, Kōichi Yamamoto, Mai Kabayama, Saori Yasumoto, Saya Terada, Takumi Hirata
article en
1 citations

Abstract

A cross-sectional analysis revealed that 52.0% of 611 participants had NT-proBNP ≥ 125 pg/mL. Multinomial logistic regression analysis showed that female sex, older age (80s and 90s), and uncontrolled high blood pressure were significantly associated with 125 ≤ NT-proBNP < 300 pg/mL, while older age (80s and 90s), coronary artery disease, atrial fibrillation, and renal dysfunction were significantly associated with NT-proBNP ≥ 300 pg/mL. Independent association between higher salt intake and NT-proBNP ≥ 300 pg/mL was also observed. Appropriate management of common HF risk factors, such as uncontrolled high blood pressure and high salt intake, is crucial to prevent the progression of overt HF.

BMC Research NotesVol. 18(1)
Osaka City University (JP), Keio University Hospital (JP), Tokyo Metropolitan Institute of Gerontology (JP), Tokyo Metropolitan Geriatric Hospital (JP), Osaka International University (JP), The University of Osaka (JP)
Japan Agency for Medical Research and Development, Ministry of Health, Labour and Welfare, Nippon Foundation, Japan Society for the Promotion of Science
Openalex Percentile: Top 19%
Heart Failure Treatment and Management
1.39
DOIOpen Access PDFOpenAlex
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