A Case of Primary Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms Tumor of the Bladder

膀胱原发的混合性神经内分泌–非神经内分泌肿瘤(mixed neuroendocrine-non-neuroendocrine neoplasms, MiNENs)非常罕见，其神经内分泌多为小细胞神经内分泌癌(small cell neuroendocrine carcinoma, SCNEC)，而非神经内分泌成分常与尿路上皮癌有关。我们描述了一例膀胱的原发性MiNENs，由SCNEC和高级别浸润性尿路上皮癌组成，并探讨了其诊断、治疗和预后。Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of bladder origin are very rare, and their neuroendocrine mostly small cell neuroendocrine carcinoma (SCNEC) and non-neuroendocrine components are often associated with uroepithelial carcinoma. We describe a case of primary MiNENs of the bladder, consisting of SCNEC and high-grade invasive uroepithelial carcinoma, and discuss its diagnosis, treatment, and prognosis.