Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

While some associations were statistically significant, the small effect sizes and lack of associations observed in the whole UK Biobank population suggest that <i>CYP3A5</i> variation likely has no impact on blood pressure related phenotypes in a general population.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-05-20
DOI
https://doi.org/10.3389/fgene.2025.1490863
Primary Topic
Eicosanoids and Hypertension Pharmacology
Type
article
Field-Weighted Citation Impact
0.00
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article

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

Julio D. Duarte, Christelle Lteif, Pia Leibold
Frontiers in Genetics
Eicosanoids and Hypertension Pharmacology
article

Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank

Julio D. Duarte, Christelle Lteif, Pia Leibold
article en

Abstract

While some associations were statistically significant, the small effect sizes and lack of associations observed in the whole UK Biobank population suggest that <i>CYP3A5</i> variation likely has no impact on blood pressure related phenotypes in a general population.

Frontiers in GeneticsVol. 16
American Association of Colleges of Pharmacy (US)
Openalex Percentile: Top 88%
Eicosanoids and Hypertension Pharmacology
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Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank — Julio D. Duarte, Christelle Lteif, et al. · Frontiers in Genetics (2025) | TGRS Research Map | TGRS