Clinical characteristics and short-term outcomes of migraine with patent foramen ovale: a comparative study
Compared to patients with MH, patients with MH-PFO have earlier symptom onset, higher rates of migraine aura, increased headache severity, more severe anxiety/depression, elevated D-dimer levels, and a greater incidence of family history of migraine. These patients respond more poorly to medication than patients with MH do. PFO closure has superior short-term efficacy in patients with migraine aura, intrinsic shunt, and high baseline HIT-6 scores (HIT-6 ≥ 59.5), highlighting the need for tailored therapeutic strategies.
Authors
- Yuxiang Sun (ORCID: https://orcid.org/0000-0002-7704-0559)
- Yan Xie (ORCID: https://orcid.org/0000-0002-2457-9382)
- Yong Luo (ORCID: https://orcid.org/0000-0002-7721-3974)
- Nanqu Huang (ORCID: https://orcid.org/0000-0002-1910-6660)
- Tao Xu (ORCID: https://orcid.org/0000-0003-1984-1689)
- Jianming Zhan (ORCID: https://orcid.org/0000-0003-2510-9515)
- Fei Feng (ORCID: https://orcid.org/0000-0002-2529-7504)
Institutions
- Zunyi Medical University (CN)
- First People’s Hospital of Zunyi (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s40001-025-02645-w
- Primary Topic
- Cardiovascular and Diving-Related Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Commission of Guizhou Province
- Recruitment Program of Global Experts