Guideline of precisional testing in intrahepatic cholangiocarcinoma: an international expert consensus
Abstract Intrahepatic cholangiocarcinoma (ICC) is a highly heterogeneous tumor. Molecular profiling serves as the foundation for personalized treatment of ICC. Comprehensive molecular testing is needed to identify more patients that are suitable for specific targeted therapies. This consensus is based on clinical data from both domestic and international sources, tailored to the Chinese context, and focuses on key targets for ICC. We present 15 recommendations aimed at guiding the precision detection of ICC.
Authors
- Xia Sheng (ORCID: https://orcid.org/0000-0002-8742-7343)
- Xuchen Zhang (ORCID: https://orcid.org/0000-0002-1484-4672)
- Hui‐Chuan Sun (ORCID: https://orcid.org/0000-0003-3761-7058)
- Hanlin L. Wang (ORCID: https://orcid.org/0000-0003-1409-5234)
- Bing Yu (ORCID: https://orcid.org/0000-0002-3421-8601)
- Ruoyu Shi (ORCID: https://orcid.org/0000-0001-8292-4044)
- Xin Zhang (ORCID: https://orcid.org/0000-0003-4298-7926)
- Бин Ли (ORCID: https://orcid.org/0000-0002-8038-0140)
- Wen‐Ming Cong (ORCID: https://orcid.org/0000-0002-8924-5551)
- Jing Han (ORCID: https://orcid.org/0000-0003-1460-0114)
- Jia Fan (ORCID: https://orcid.org/0000-0001-5158-629X)
- Jian Zhou (ORCID: https://orcid.org/0000-0002-2118-1117)
- Zengshan Li
- Yuan Ji (ORCID: https://orcid.org/0000-0002-2631-9082)
- Guo‐Ming Shi (ORCID: https://orcid.org/0000-0003-3446-7875)
- Yining Zou
Institutions
- Army Medical University (CN)
- Sun Yat-sen University (CN)
- University of California, Los Angeles (US)
- Second Military Medical University (CN)
- Singapore General Hospital (SG)
- Fudan University (CN)
- Royal Prince Alfred Hospital (AU)
- Yale University (US)
- Minhang District Central Hospital (CN)
- Xi'an Medical University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Bulletin
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1007/s44272-025-00036-0
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Commission of Shanghai Municipality