EFFECTS OF A FAT DIET ON THE BLOOD CELLS OF THE RAT BRAIN

The purpose of this article was to establish the nature of changes in the blood vessels of the brain under the influence of a fat diet. The effects of diet on the brain are the most controversial compared to other organs. At the same time, it is known that any changes in the brain occur around the «vessel – astrocyte – neuron» microaxis. At the same time, the leading role is played by the blood vessel at the level of microhemocirculation, where the continuous unity of blood supply, metabolism and neurohumarolic regulation is most clearly manifested. For a long time, it was believed that metabolism in the brain is glycocentric, insulin-independent, aerobic. Only in recent years has there been information about the possibility of metabolism in the brain along the lipocentric pathway, in which glycolysis slows down and lipolysis and B-oxidation of fatty acids are activated.

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Publication Details

Journal
Vestnik of the Kyrgyz-Russian Slavic University
Published
2025-01-01
DOI
https://doi.org/10.36979/1694-500x-2025-25-1-146-151
Primary Topic
Adipose Tissue and Metabolism
Type
article
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article

EFFECTS OF A FAT DIET ON THE BLOOD CELLS OF THE RAT BRAIN

Аssel B. Altynbekova, Elmira Mamytova, Ortiz de Apodaca A, Aycholpon Israilova et al.
Vestnik of the Kyrgyz-Russian Slavic University
Adipose Tissue and Metabolism
article

EFFECTS OF A FAT DIET ON THE BLOOD CELLS OF THE RAT BRAIN

Аssel B. Altynbekova, Elmira Mamytova, Ortiz de Apodaca A, Aycholpon Israilova, Bolotbek Alymzhan uulu, Yu.Kh.-M. Shidakov, Aizhanat Nurbek kyzy
article en

Abstract

The purpose of this article was to establish the nature of changes in the blood vessels of the brain under the influence of a fat diet. The effects of diet on the brain are the most controversial compared to other organs. At the same time, it is known that any changes in the brain occur around the «vessel – astrocyte – neuron» microaxis. At the same time, the leading role is played by the blood vessel at the level of microhemocirculation, where the continuous unity of blood supply, metabolism and neurohumarolic regulation is most clearly manifested. For a long time, it was believed that metabolism in the brain is glycocentric, insulin-independent, aerobic. Only in recent years has there been information about the possibility of metabolism in the brain along the lipocentric pathway, in which glycolysis slows down and lipolysis and B-oxidation of fatty acids are activated.

Vestnik of the Kyrgyz-Russian Slavic UniversityVol. 25(1)
Openalex Percentile: Top 85%
Adipose Tissue and Metabolism
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