THE STRUCTURE OF THE PITUITARY GLAND IN THE HIGHLANDS DURING MYOCARDIAL INFARCTION

The structure of pituitary gland in catecholamine cardionecrosis in animals in different terms of mountain adaptation was studied. The studies were carried out on sexually mature male rats in the high mountains of Kyrgyzstan, 3200 m above sea level (Too-Ashuu pass). The animals were divided into two groups: control group (10 animals) - animals kept in vivarium conditions in the high mountains, Too-Ashuu Pass (Kyrgyzstan), 3200 m above sea level; experimental group (10 animals) - animals with experimental myocardial infarction. Catecholamine necroses were provoked by injection into the abdominal cavity, administration of a toxic dose of sol. Adrenalini hidrochloridi 0.1% at the rate of 0.25 ml per 100 g of animal body weight. The pituitary gland was sampled on the 15th day, fixed in 10% neutral formalin with subsequent pouring into paraffin. Sections were stained by Van-Gizon staining. The study revealed that in myocardial infarction in high altitude conditions there are changes in the structure of pituitary gland, such as pericellular and perivascular edema, vascular hemorrhage, which is characterized by the fact that the hormonal background of the organism changes.