Stereotactic ablative radiotherapy for patients with hepatocellular carcinoma: analysis of post-treatment radiology and explant histology
In our case series conventional radiological criteria underestimated HCC tumour viability following SABR compared to explant histology. As the role for SABR expands in the management of HCC, caution is needed with radiological interpretation of HCC responses to radiotherapy using standard LI-RADS criteria. Prospective study in a larger cohort is required to identify radiological criteria capable of more conclusively evaluating HCC responses to SABR.
Authors
- Ramanivas Sundareyan (ORCID: https://orcid.org/0000-0002-8906-8890)
- Nekisa Zakeri (ORCID: https://orcid.org/0000-0003-1167-1160)
- Shishir Shetty (ORCID: https://orcid.org/0000-0002-4729-2173)
- Tahir Shah (ORCID: https://orcid.org/0000-0002-0420-0304)
- Lorna Cain (ORCID: https://orcid.org/0000-0002-7907-3856)
- James Good
Institutions
- Queen Elizabeth Hospital Birmingham (GB)
- NIHR Birmingham Biomedical Research Centre (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- BJC Reports
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1038/s44276-025-00136-3
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- Birmingham Biomedical Research Centre