Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating <scp>natriuretic peptide B</scp>
The cardiovascular protective effect of Cana in diabetes mellitus was mediated by upregulating the expression of NPPB and upregulating the level of PKG1α, which in turn regulated the viability, apoptosis rate, and ROS level of AC16 cells.
Authors
- Xiaopei Wu (ORCID: https://orcid.org/0000-0003-2731-1776)
- Lichenlu Huang
- Jiarui Zhang (ORCID: https://orcid.org/0009-0005-2474-6952)
- Jun-Dong He (ORCID: https://orcid.org/0000-0002-6601-1373)
- Yongqin Zheng (ORCID: https://orcid.org/0000-0001-8383-848X)
- Ji Yang (ORCID: https://orcid.org/0000-0001-8659-4206)
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1111/jdi.70056
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00