Phenylketonuria Associated Early Onset Parkinsonism: A Case of Rapid Progression Following Dietary Nonadherence
Introduction: Early-onset Parkinsonism is a rare complication of phenylketonuria (PKU), a metabolic disorder marked by elevated phenylalanine and reduced tyrosine levels. This biochemical imbalance leads to dopamine deficiency in the basal ganglia, contributing to
Authors
- Nethmi Weerasinghe
- Marina Janelidze (ORCID: https://orcid.org/0000-0001-7209-0090)
- Achille Peiris
- Irine Khatiashvili
- Nino Tchikadze
Institutions
- National University of Technology (PK)
- Tbilisi State Medical University (GE)
Publication Details
- Journal
- JUNIOR RESEARCHERS
- Published
- 2025-05-19
- DOI
- https://doi.org/10.52340/jr.2025.03.02.07
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00