Chromatin accessibility and transcriptomic profiles of sheep pituitary function associated with fecundity
This study systematically delineated the gene expression and chromatin accessibility of the pituitary and identified some key regulatory genes associated with gonadotropin secretion in sheep. Our integrated multi-omics analysis identifies critical molecular markers that may contribute to the genetic improvement of reproductive efficiency in ovine species.
Authors
- Peiyong Chen (ORCID: https://orcid.org/0009-0002-6475-359X)
- Bingru Zhao (ORCID: https://orcid.org/0009-0004-0140-8654)
- Shanglai Li
- Chenbo Yan (ORCID: https://orcid.org/0000-0002-5061-5041)
- Yu Cai (ORCID: https://orcid.org/0000-0001-8804-2616)
- Hui Xu (ORCID: https://orcid.org/0000-0003-3424-1219)
- Yanli Zhang (ORCID: https://orcid.org/0000-0002-7901-7774)
- Feng Wang
Institutions
- Nanjing Agricultural University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s12864-025-11621-x
- Citations
- 1
- Primary Topic
- Genetic and phenotypic traits in livestock
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Government of Jiangsu Province
- Nanjing Agricultural University
- National Key Research and Development Program of China