Toxoplasma calcium-dependent protein kinases 3 mediates M1 macrophage polarization by targeting host Arginase-1
Our data showed that CDPK3 mediates M1 macrophage polarization by targeting host Arginase-1, which is beneficial to understanding the mechanism for long term latency establishment of less virulent strains of Toxoplasma.
Authors
- Jian Du (ORCID: https://orcid.org/0000-0001-5010-7859)
- N. Dai
- Haijian Cai
- Ran An (ORCID: https://orcid.org/0000-0002-2417-0552)
- Fang Liu (ORCID: https://orcid.org/0000-0002-8325-1213)
- Xingyun Liu (ORCID: https://orcid.org/0000-0002-9295-2767)
- Fangmin Li (ORCID: https://orcid.org/0009-0003-6949-204X)
- Lijian Chen (ORCID: https://orcid.org/0000-0003-0627-1138)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s13071-025-06799-8
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China