Fc-effector functional antibody assays for SARS-CoV-2 variants of concern
The COVID-19 XBB.1.5 booster vaccination significantly improved the magnitude, breadth, and quality of antibody responses to SARS-CoV-2. Combining Fc-mediated functional and neutralizing antibody assays provides a more comprehensive model for understanding vaccine-induced immunity and optimizing vaccination strategies.
Authors
- Caroline Ciric
- Theda Gibson
- Christina A. Rostad (ORCID: https://orcid.org/0000-0001-8439-0592)
- Grace Li (ORCID: https://orcid.org/0000-0002-6661-0421)
- Xuemin Chen (ORCID: https://orcid.org/0000-0002-1818-9206)
- Larry J. Anderson
Institutions
- Emory University (US)
- Children's Healthcare of Atlanta (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1571835
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Emory University