Exploring the standardized detection and sampling methods of human nasal SARS-CoV-2 RBD IgA
This study has established the first standardized nasal detection system. The system can be adapted with appropriate modifications for the clinical evaluation of other respiratory mucosal vaccines, thereby advancing the development of mucosal vaccines.
Authors
- Jianping Chu
- Chaoying Hu (ORCID: https://orcid.org/0000-0002-0116-4387)
- Guanxing Liu
- Jizong Jia
- Na Li (ORCID: https://orcid.org/0000-0003-3619-7899)
- Lina Wang (ORCID: https://orcid.org/0000-0003-1457-0015)
- Fan Gao (ORCID: https://orcid.org/0000-0002-2828-256X)
- Yajing Li (ORCID: https://orcid.org/0009-0001-6296-7394)
- Qian He
- Hui Zhao (ORCID: https://orcid.org/0000-0003-0576-1012)
- Zhenglun Liang (ORCID: https://orcid.org/0000-0002-6740-0864)
- Zhihao Fu (ORCID: https://orcid.org/0009-0009-6116-0589)
- Qunying Mao
- Jingxin Li (ORCID: https://orcid.org/0009-0001-7168-6287)
- Miao Xu
- Hao Xu (ORCID: https://orcid.org/0009-0000-1851-6118)
- Xuanxuan Zhang
Institutions
- Shenyang Pharmaceutical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Medical Products Administration (CN)
- Changchun Institute of Biological Products (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- National Institutes for Food and Drug Control (CN)
- Beijing Wantai Biological Pharmacy (China) (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1571418
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Institutes for Food and Drug Control
- Government of Jiangsu Province