Randomized trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain: 540 mg <i>vs</i> . 900 mg dose comparison
The PK of menthol derived from PMO demonstrates apparent dose-proportionality, and gut transit and contractility are associated with the systemic concentration of menthol.
Authors
- Salma Musaad (ORCID: https://orcid.org/0000-0003-1733-830X)
- Gregory L. Kearns (ORCID: https://orcid.org/0000-0001-5546-429X)
- Jiali Wen (ORCID: https://orcid.org/0000-0002-9173-9665)
- Bruno P. Chumpitazi (ORCID: https://orcid.org/0000-0002-0829-0036)
- Robert J. Shulman (ORCID: https://orcid.org/0000-0003-2385-0991)
- Uttam Garg
Institutions
- University of North Carolina at Chapel Hill (US)
- Texas Christian University (US)
- Children's Mercy Hospital (US)
- Duke University (US)
- Baylor College of Medicine (US)
- Clinical Research Institute (US)
- Children's Nutrition Research Center at Baylor College of Medicine (US)
- Texas Children's Hospital (US)
- University of Missouri (US)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/bcp.70097
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81
Funders
- Agricultural Research Service
- National Center for Complementary and Integrative Health