LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis
OIP5-AS1 modulates macrophage polarization through the miR-429/DOCK4 axis and inhibits LUAD cell progression. This regulatory pathway may influence the tumor immune microenvironment and represent a potential therapeutic target in LUAD.
Authors
- Dan Xiao (ORCID: https://orcid.org/0009-0008-0042-3763)
- Yuhua Wang (ORCID: https://orcid.org/0000-0003-3138-1312)
- Runze Li (ORCID: https://orcid.org/0000-0003-2543-3032)
- Yihan Liu (ORCID: https://orcid.org/0000-0001-9094-0693)
- Long Cui (ORCID: https://orcid.org/0000-0001-8141-0914)
Institutions
- Qiqihar University (CN)
- Harbin Engineering University (CN)
- Heilongjiang University of Chinese Medicine (CN)
- Harbin Institute of Technology (CN)
- Qiqihar Institute of Engineering (CN)
- Qiqihar Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.3389/fphar.2025.1569644
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Natural Science Foundation of China