Unraveling the causal pathway between phosphatidylinositol, metabolites, and metabolic syndrome: a Mendelian randomization study
Our MR analysis demonstrated a positive association between PI and an increased risk of MetS. Furthermore, the metabolite-mediated PI significantly influenced MetS risk. These findings may offer valuable insights into the pathogenesis of MetS and inform future clinical research.
Authors
- Ming D. Li (ORCID: https://orcid.org/0000-0002-6873-9472)
- Yubo Han (ORCID: https://orcid.org/0000-0001-5251-0721)
- Yanchun Yang (ORCID: https://orcid.org/0000-0001-6974-6175)
- Li Liu (ORCID: https://orcid.org/0000-0003-0527-9250)
- Yanling Ma (ORCID: https://orcid.org/0000-0001-9025-1804)
Institutions
- Heilongjiang University of Chinese Medicine (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s13098-025-01731-7
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Heilongjiang University
- National Natural Science Foundation of China