<i>Salvia miltiorrhiza</i> -derived exosome-like nanoparticles improve diabetic cardiomyopathy by inhibiting NLRP3 inflammasome-mediated macrophage pyroptosis via targeting the NEDD4/SGK1 axis
Our study provides the first evidence that SM-ELNs inhibit NLRP3 inflammasome-mediated macrophage pyroptosis in DCM by modulating the NEDD4/SGK1 axis.
Authors
- Zhenfeng Gong (ORCID: https://orcid.org/0000-0002-8582-7335)
- Bin Deng (ORCID: https://orcid.org/0000-0002-6110-399X)
- Xiaoduo Zhang
- Jialiang Lin (ORCID: https://orcid.org/0000-0001-9067-6423)
- Peng Zhijian
- Zhiyong Wang
Institutions
- Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Nanomedicine
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1080/17435889.2025.2506351
- Citations
- 6
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.84