Fibrosis in the Hiatus of Esophagus in Patients With Primary Esophageal Motor Disorders: Radiomic Analysis
A higher GSI of the hiatus with greater overlap between the hiatus and muscle suggests an increase in fibro-connective tissue in the esophageal hiatus of patients with primary esophageal motility disorders (EMD). We propose that fibrosis in the esophageal hiatus restricts axial separation between the LES and crural diaphragm, which may be important in the pathogenesis of esophageal motor disorders.
Authors
- Ravinder K. Mittal (ORCID: https://orcid.org/0000-0001-5228-9617)
- A. Sharma (ORCID: https://orcid.org/0009-0004-1702-7485)
- Paul C. Stark
- J. Fu (ORCID: https://orcid.org/0000-0002-7257-384X)
- Ali Zifan (ORCID: https://orcid.org/0000-0003-0272-7492)
- Shreeya Candipali
- Carlos Nemeh
- Lixin Sun
- Anant Gupta
Institutions
- University of California San Diego (US)
- University of California San Diego Medical Center (US)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1111/nmo.70085
- Citations
- 2
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.62
Funders
- National Institutes of Health