Atopobium vaginae: An Overview of the Bacteria Through Clinical Cases

Atopobium vaginae (nowadays Fannyhessea vaginae) is an anaerobic bacterium increasingly implicated not only in bacterial vaginosis (BV) but also in a broader range of infections. Despite growing recognition of its clinical relevance, comprehensive data on the characteristics of A. vaginae remain limited. This study aimed to isolate and thoroughly characterize the clinical strains of A. vaginae from both vaginal and oral cavity samples. A multifaceted methodological approach was employed, including antibiotic susceptibility testing to assess resistance and sensitivity profiles, PCR for genetic identification, and biochemical profiling using the VITEK-2 Compact system. Additionally, the morphological traits and growth dynamics of the isolates were examined. Given the established role of A. vaginae as a significant contributor to BV, the results of this study aim to support the development of evidence-based antimicrobial strategies for effective management of A. vaginae-associated infections.