Current status and future direction of antimicrobial stewardship programs and antibiotic prescribing in primary care hospitals in Zambia
ASP implementation in Zambia's FLHs providing PHC was sub-optimal, with high antibiotic prescribing rates, frequent use of broad-spectrum Watch group antibiotics, and low compliance with national treatment guidelines. As key ways forward, ASPs in Zambia's PHC require strengthening by adapting the WHO AWaRe recommendations and improving accountability, actions, tracking, and reporting antibiotic use to improve stewardship practice and reduce AMR.
Authors
- Melanie J. Newport (ORCID: https://orcid.org/0000-0002-8946-7525)
- Steward Mudenda (ORCID: https://orcid.org/0000-0003-1692-8981)
- Martin Kampamba (ORCID: https://orcid.org/0000-0003-0730-3795)
- Duncan Chanda (ORCID: https://orcid.org/0000-0001-5477-9054)
- Mirfin Mpundu (ORCID: https://orcid.org/0000-0001-8863-0995)
- Flavien Nsoni Bumbangi (ORCID: https://orcid.org/0000-0002-0731-3558)
- Raphael Chanda
- Aubrey Chichonyi Kalungia (ORCID: https://orcid.org/0000-0003-2554-1236)
- Chileshe Lukwesa
- Derick Munkombwe (ORCID: https://orcid.org/0009-0006-8219-0777)
- Chiluba Mwila (ORCID: https://orcid.org/0000-0003-0160-1222)
- Joseph Yamweka Chizimu (ORCID: https://orcid.org/0000-0002-2126-5759)
- Zoran Muhimba
- Israel Abebrese Sefah (ORCID: https://orcid.org/0000-0001-6963-0519)
- Maisa Kasanga (ORCID: https://orcid.org/0000-0003-1724-7934)
- Natalie Schellack (ORCID: https://orcid.org/0000-0001-9690-6285)
- Roma Chilengi (ORCID: https://orcid.org/0000-0003-0221-9527)
- Freddie Masaninga (ORCID: https://orcid.org/0000-0002-4040-1736)
- Michael Okorie (ORCID: https://orcid.org/0000-0003-1960-8860)
- Ilunga Mutwale
- Johanna Catharina Meyer
- Brian Godman
- David Banda
- Faustina Makiko
- Anja St Claire-Jones
Institutions
- Brighton and Sussex Medical School (GB)
- Ministry of Health (ZM)
- University of Sussex (GB)
- St George's, University of London (GB)
- University of Strathclyde (GB)
- University of Health and Allied Sciences (GH)
- Sefako Makgatho Health Sciences University (ZA)
- University Teaching Hospital (ZM)
- University of Zambia (ZM)
- CNR de la Résistance aux Antibiotiques (FR)
- World Health Organization - Zambia (ZM)
- University Hospitals Sussex NHS Foundation Trust (GB)
- City St George's, University of London (GB)
- University of Pretoria (ZA)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1093/jacamr/dlaf085
- Citations
- 4
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 5.05
Funders
- National Institutes of Health
- National Cancer Institute