Results of plate osteosynthesis of the femur at the patient with osteogenesis imperfecta

Osteogenesis imperfecta is a rare disease characterized by bone fragility, frequent fractures, bone deformities, and low bone mineral density. The relative risk of bone fractures in patients with osteogenesis imperfecta is 4–6 times higher than in the general population. In adult patients with osteogenesis imperfecta, the incidence of femoral shaft fractures is approximately 35 times higher than in the general population. According to modern literature data, the preferred method of osteosynthesis in such patients is intramedullary. Osteosynthesis with plates is associated with a high incidence of complications. A case of treatment of a patient with osteogenesis imperfecta who underwent two femoral osteosynthesis operations with plates at an interval of 2.5 years is presented. The first operation was performed for a femoral shaft fracture at the height of varus deformity. The second osteosynthesis was performed for a peri-implant fracture of the proximal femur. Femoral consolidation was achieved at both levels. The presented case demonstrates that plate osteosynthesis can be effective in the treatment of femoral fractures in patients with osteogenesis imperfecta, achieving consolidation if the described surgical nuances are observed

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Journal
Osteoporosis and Bone Diseases
Published
2025-05-17
DOI
https://doi.org/10.14341/osteo13189
Primary Topic
Connective tissue disorders research
Type
article
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article

Results of plate osteosynthesis of the femur at the patient with osteogenesis imperfecta

В. П. Волошин, K.V. Shevyrev, D. A. Shavyrin, Elena V. Proskurina et al.
Osteoporosis and Bone Diseases
Connective tissue disorders research
article

Results of plate osteosynthesis of the femur at the patient with osteogenesis imperfecta

В. П. Волошин, K.V. Shevyrev, D. A. Shavyrin, Elena V. Proskurina, D. V. Martynenko, R. V. Kondaleva, M. A. Shakhova
article en

Abstract

Osteogenesis imperfecta is a rare disease characterized by bone fragility, frequent fractures, bone deformities, and low bone mineral density. The relative risk of bone fractures in patients with osteogenesis imperfecta is 4–6 times higher than in the general population. In adult patients with osteogenesis imperfecta, the incidence of femoral shaft fractures is approximately 35 times higher than in the general population. According to modern literature data, the preferred method of osteosynthesis in such patients is intramedullary. Osteosynthesis with plates is associated with a high incidence of complications. A case of treatment of a patient with osteogenesis imperfecta who underwent two femoral osteosynthesis operations with plates at an interval of 2.5 years is presented. The first operation was performed for a femoral shaft fracture at the height of varus deformity. The second osteosynthesis was performed for a peri-implant fracture of the proximal femur. Femoral consolidation was achieved at both levels. The presented case demonstrates that plate osteosynthesis can be effective in the treatment of femoral fractures in patients with osteogenesis imperfecta, achieving consolidation if the described surgical nuances are observed

Osteoporosis and Bone DiseasesVol. 28(1)
Regional Clinical Research (US)
Openalex Percentile: Top 87%
Connective tissue disorders research
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Results of plate osteosynthesis of the femur at the patient with osteogenesis imperfecta — В. П. Волошин, K.V. Shevyrev, et al. · Osteoporosis and Bone Diseases (2025) | TGRS Research Map | TGRS