Primary Retroperitoneal Mucinous Cystadenocarcinoma in a Male Patient: A Rare Surgical Case Report

Introduction and Importance: Primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is a rare entity, particularly in male patients. Its origin remains uncertain and presents a diagnostic challenge. Case Presentation: A 48 -year -old male with progressive abdominal distension over three months. CT imaging revealed a well -circumscribed, multilocular cystic mass in the left retroperitoneal space measuring 15 12 10 cm. The patient underwent complete surgical excision of the mass. Histopathology confirmed mucinous cystadenocarcinoma with positive immunohistochemical staining for CK7 and CEA. The patient recovered uneventfully and remained recurrence -free at six -month follow -up. Clinical Discussion: PRMCs are rarely seen in males. Their origin may involve metaplastic transformation of mesothelial or Mllerian remnants. Preoperative diagnosis is challenging due to overlapping imaging features with benign cystic lesions. Surgical resection is both diagnostic and therapeutic. Conclusion: PRMC should be considered in the differential diagnosis of retroperitoneal cystic masses, even in male patients. Early surgical intervention remains key to favorable outcomes.