Downstream branches of receptor tyrosine kinase signaling act interdependently to shape the face
Since RTK signaling is a ubiquitous and tightly regulated biochemical system, we conclude that the downstream pathways are robust to developmental perturbation through redundant signaling systems.
Authors
- Ralph Marcucio (ORCID: https://orcid.org/0000-0002-0537-818X)
- Benedikt Hallgrímsson (ORCID: https://orcid.org/0000-0002-7192-9103)
- Marta Vidal‐García (ORCID: https://orcid.org/0000-0001-7617-7329)
- Nicholas J. Hanne (ORCID: https://orcid.org/0000-0002-3715-6768)
- Wei Liu (ORCID: https://orcid.org/0000-0002-9302-8170)
- Diane Hu
- M. Bilal Shakir
- Charlie Allen
Institutions
- University of Calgary (CA)
- University of California, San Francisco (US)
- Alberta Children's Hospital (CA)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1002/dvdy.70041
- Citations
- 1
- Primary Topic
- Fibroblast Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Canada Foundation for Innovation
- Canada First Research Excellence Fund
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada
- National Institute of Dental and Craniofacial Research