COMBINATIONS OF ISONIAZID, PYRAZINAMIDE, RIFAMPICIN AND ETHAMBUTOL AS PART OF AN ANTI-TUBERCULOSIS DRUG CONTAINING AND NOT CONTAINING PYRIDOXINE HYDROCHLORIDE

The article contains the results of a comparative experimental Toxicological studies of the combined (hybrid) containing anti-TB drugs: isoniazid, pyrazinamide, rifampicin, ethambutol hydrochloride and pyridoxine hydrochloride (vitamin B6) as part of a single dosage form, which allowed to establish the fact of a decrease of toxicity with the drug containing pyridoxine hydrochloride in relation to the preparation without pyridoxine hydrochloride.