Subretinal delivery of AAV5-mediated human <i>Pde6b</i> gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa.

Our results demonstrate that AAV5-<i>Pde6b</i> may be a potential therapeutic gene candidate for RP caused by <i>Pde6b</i> mutations.

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PubMed
Published
2025-01-01
Primary Topic
Retinal and Optic Conditions
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article
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article

Subretinal delivery of AAV5-mediated human Pde6b gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa.

Heuiran Lee, Jae‐Man Kwak, Joo Yong Lee, Hee Jong Kim et al.
PubMed
Retinal and Optic Conditions
article

Subretinal delivery of AAV5-mediated human Pde6b gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa.

Heuiran Lee, Jae‐Man Kwak, Joo Yong Lee, Hee Jong Kim, So-Yoon Won, Jun Sub Choi, Jin Kim, Seo Yun Moon, Steven Hyun Seung Lee, Keerang Park
article en

Abstract

Our results demonstrate that AAV5-<i>Pde6b</i> may be a potential therapeutic gene candidate for RP caused by <i>Pde6b</i> mutations.

PubMedVol. 31
University of Ulsan (KR)
Openalex Percentile: Top 82%
Retinal and Optic Conditions
Open Access PDFOpenAlex
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Subretinal delivery of AAV5-mediated human <i>Pde6b</i> gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa. — Heuiran Lee, Jae‐Man Kwak, et al. · PubMed (2025) | TGRS Research Map | TGRS