Astragaloside IV improves the survival rates of retinal ganglion cells in traumatic optic neuropathy by regulating autophagy mediated by the AMPK-MTOR-ULK signaling pathway.
AS-IV can increase the survival rate of RGCs and improve visual function after TON, which may be related to the improvement of autophagy by regulating the AMPK-MTORC1-ULK pathway.
Authors
- Guojun Chao (ORCID: https://orcid.org/0000-0002-2341-3735)
- Mengqiu Shang (ORCID: https://orcid.org/0000-0002-8119-362X)
- Yanting Xia
- Qi-Ping Wei (ORCID: https://orcid.org/0009-0000-1369-7415)
- Jian Zhou (ORCID: https://orcid.org/0000-0001-7800-881X)
- Wu Sun (ORCID: https://orcid.org/0000-0002-1638-9861)
- Qiong Wu (ORCID: https://orcid.org/0000-0002-9048-9094)
- Liang Liao (ORCID: https://orcid.org/0000-0002-7390-4540)
Institutions
- Beijing Tongren Hospital (CN)
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- Citations
- 1
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.71