A resistant case of chloracne successfully treated with azithromycin pulse

Chloracne is a rare disorder that presents as an acneiform eruption in patients working in the chlorine industry. Diagnosis of chloracne is difficult, mainly based on clinical history, temporal correlation, clinical manifestation, and biopsy along with immunohistochemistry. Treatment includes doxycycline and isotretinoin, which show variable results. Here, I report a case of chloracne in a patient working as a chlorophenol and chlorobenzene handler who showed no improvement with isotretinoin therapy and later completely improved with an azithromycin pulse.