Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients
Overall, our findings support LDN as a potentially beneficial treatment for long COVID patients by restoring TRPM3 ion channel function and reestablishing adequate Ca<sup>2+</sup> influx necessary for homeostatic cellular processes.
Authors
- Peter Smith (ORCID: https://orcid.org/0000-0002-2629-8963)
- Etianne Martini Sasso (ORCID: https://orcid.org/0000-0003-1552-5101)
- Katsuhiko Muraki (ORCID: https://orcid.org/0000-0002-4779-6494)
- Sonya Marshall‐Gradisnik (ORCID: https://orcid.org/0000-0001-9270-2437)
- Natalie Eaton-Fitch (ORCID: https://orcid.org/0000-0002-0815-3162)
Institutions
- Griffith University (AU)
- Aichi Gakuin University (JP)
- Gold Coast Health (AU)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fmolb.2025.1582967
- Citations
- 4
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 5.56