Aberrant expression of PYGB as a potential therapeutic target and its associations with immune cell infiltration in lung cancer
This study unveils that elevated PYGB expression in LC is significantly correlated with poor prognosis, potentially attributable to PYGB's facilitation of LC cell proliferation, migration, and metastasis, as well as its significant association with the immune microenvironment.
Authors
- Dong Xu (ORCID: https://orcid.org/0000-0002-6413-3043)
- Kai Sun (ORCID: https://orcid.org/0000-0001-6562-7670)
- Fangfang Xie (ORCID: https://orcid.org/0000-0003-2668-460X)
- Xia Qin (ORCID: https://orcid.org/0000-0003-0412-0352)
Institutions
- Ganzhou People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1536248
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00