Hypericin Regulates Inflammation Levels and Improves Depressive Symptoms in Rats With Post‐Stroke Depression Through the MEK/ERK/CREB Pathway
Hypericin promotes M2 microglial polarisation, reduces inflammation and improves depressive behaviour in PSD rats by activating the MEK/ERK/CREB pathway.
Authors
- Kui Jia
- Wenlong Li (ORCID: https://orcid.org/0000-0003-3564-1708)
- Yifan Li (ORCID: https://orcid.org/0000-0001-9950-0037)
- Lingling Qian (ORCID: https://orcid.org/0000-0002-3806-3109)
Institutions
- First Affiliated Hospital of Xinxiang Medical University (CN)
- First Affiliated Hospital of Henan University (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Journal of Biochemical and Molecular Toxicology
- Published
- 2025-05-18
- DOI
- https://doi.org/10.1002/jbt.70295
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84