Making safety decisions for a sunscreen active ingredient using next-generation risk assessment: Benzophenone-4 case study_suppl2

Tab. S1: Summary of assays in the In vitro Pharmacological Profiling (IPP) panel, assay type, and associated ligand/control Assay name Ligand / control Assay type Monoamine oxidase type A, MAOA (r) (antagonist radioligand) clorgyline Binding Androgen receptor, AR (h) (agonist radioligand) testosterone Binding Muscarinic acetylcholine receptor M1, CHRM1 (h) (antagonist radioligand) pirenzepine Binding Endothelin-1 receptor, EDNRA (h) (agonist radioligand) endothelin-1 Binding Glucocorticoid receptor, NR3C1 (h) (agonist radioligand) dexamethasone Binding Histamine H2 receptor, HRH2 (h) (antagonist radioligand) cimetidine