Synergistic Effects of Cryotherapy and Radiotherapy in Glioblastoma Treatment: Evidence from a Murine Model
These findings suggest that cryotherapy may enhance radiotherapy efficacy, resulting in complete tumor regression in 4 out of 10 cases. ADC distribution may serve as a predictive marker for therapeutic response. However, given the limitations of the model, further studies in orthotopic models are needed to validate these findings and assess their clinical relevance.
Authors
- Chrystelle Po (ORCID: https://orcid.org/0000-0001-9785-9572)
- Marion Rame
- F. Proust (ORCID: https://orcid.org/0000-0003-0845-4923)
- Afshin Gangi (ORCID: https://orcid.org/0000-0002-0952-7760)
- Benoît Lhermitte (ORCID: https://orcid.org/0000-0002-4884-3758)
- Roberto Luigi Cazzato
- H. Cébula (ORCID: https://orcid.org/0000-0002-5868-3591)
- Carole Mura (ORCID: https://orcid.org/0000-0003-0305-711X)
- Clara Le Fèvre
- Charles-Henry Mallereau (ORCID: https://orcid.org/0000-0002-8747-7332)
- Michel de Mathelin (ORCID: https://orcid.org/0000-0002-8422-572X)
- Hélène Burckel (ORCID: https://orcid.org/0000-0002-9612-5806)
- Julien Todeschi
- Georges Noël (ORCID: https://orcid.org/0000-0003-4952-5572)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Institut de Cancérologie Strasbourg (FR)
- Laboratoire de Biophotonique et Pharmacologie (FR)
- Hôpital d'Hautepierre (FR)
- Hôpital Civil, Strasbourg (FR)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Cancers
- Published
- 2025-05-17
- DOI
- https://doi.org/10.3390/cancers17101692
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Agence Nationale de la Recherche
- European Regional Development Fund